Document Details

Document Type : Project 
Document Title :
Quantization of Phenolic, Squalene and Measuring the Antioxidant Potential of Different Types of Olive Oils Local vs Imported
تقدير الفينولات، السكوالين، وقياس احتمالية
 
Subject : Quantization of Phenolic, Squalene and Measuring the Antioxidant Potential of Different Types of Olive Oils Local vs Imported 
Document Language : Arabic 
Abstract : This study concentrates on the chemoprevention of cancer as a result of the health benefits of the Mediterranean diet, of which olive oil is a major component. Recent studies have shown that olive oil contains an abundance of phenolic antioxidants including simple phenols (hydroxytyrosol, tyrosol), aldehydic secoiridoids, flavonoids and lignans (acetoxypinoresinol, pinoresinol). All these phenolic substances are potent inhibitors of reactive oxygen species attack on, e.g. salicylic acid, 2-deoxy-guanosine. Currently there is growing evidence that reactive oxygen species are involved in the etiology of fat-related neoplasms such as cancer of the breast and colorectal. A plausible mechanism is a high intake of ω-6 polyunsaturated fatty acids which are especially prone to lipid peroxidation initiated and propagated by reactive oxygen species, leading to formation (via, α, β-unsaturated aldehydes such as trans-4-hydroxy-2-nonenal) of highly pro-mutagenic exocyclic DNA adducts. Previous studies have shown that the colonic mucosa of cancer patients and those suffering from predisposing inflammatory conditions such as ulcerative colitis and Crohn's disease generates appreciable higher quantities of reactive oxygen species compared with normal tissue. In our ongoing cancer chemopreventive and human health studies, we have a particular interest in the health benefit of olive oil, and therefore the aim of this study is not only to quantitate the phenolic and squalene content of different types of olive oils locally found and compared to different imported types, but also to asses their antioxidant potential. By doing this project, our laboratory will be one of center in Saudi Arabia that will be able to participate in solving any problems related to the health benefits of olive oil. 
Publishing Year : 1428 AH
2007 AD
 
Sponsor Name : King Abdulaziz University 
Sponsorship Year : 1428 AH
2007 AD
 
Added Date : Monday, July 12, 2010 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
طه عبدالله قمصانيKumosani, Taha AbdullahInvestigatorDoctorate 

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